The handcuffs in dreams is known as the bad omen. If you dream that you are in hand cuffs, then such dream shows some situation or relationships you are out of control. Perhaps you feel that you do not manage your life anymore, because your hand are handcuffed. You feel that you have no power to make decisions and be in control. The handcuffs could also show the apprehension you are suffering from, because you are afraid that you will not succeed. If you see other people being in handcuffs, then it shows you are being egoistic and thinking only about yourself.
Read more about dreaming of Handcuffs in other dream meanings interpretations.