The significance of this dream depends on how the skein is seen in the dream. If you see an unrolled skein, then it indicates that you are sensing a new activity that involves a lot of work ahead. Also its usually a harbinger of complications if you are trying to look for the tip of the skein and you are not able to find it.
Dream dictionary: skein dream meanings
Always announces messes and muddles, unless the thread is silk, in which case our good qualities will enable us to solve all problems and achieve wealth sooner or later.